Univariate Cox regression analysis showed that in the OSCC cohort, advanced tumor size (HR = 1.349, p = 0.0003), nodal status (HR = 2.168, p = 0.007), advanced tumor stage (HR = 2.892, p = 0.0000001), and recurrence status (HR = 17.245, p = 0.0000001), along with the altered expression of the FOXP3 gene (HR = 0.252, p = 0.001) and the miR-155 gene (HR = 2.388, p = 0.009), were the risk factors for poor survival in these patients. Here, FOXP3 is linked to neoplasm.