Polymorphisms in the 3′-untranslated region (UTR) of the PD-L1 gene, such as rs822336 (G>C) and rs4143815 (C>G), have been associated with the expression and prognosis of PD-L1 in non-small cell lung cancer (NSCLC) [30,31]. Here, CD274 is linked to non-small cell lung carcinoma.