Our data mining approach focused on identifying miRNAs that are known to be dysregulated in CRC and also known to target genes involved in adiponectin signaling, such as ADIPOR1, ADIPOR2, APPL1, and AMPK subunit genes, without relying on prior knowledge of evidence regarding the role of these miRNAs in CRC progression. Here, ADIPOR1 is linked to colorectal carcinoma.