High CNOT7 serum levels were associated with BMI, post-menopausal status, receiving neoadjuvant chemotherapy before surgery, late tumor stages (III/IV), greater lymph node (LN) involvement, basal and human epidermal growth factor receptor 2 (HER-2)-enriched subtypes, and estrogen receptor (ER) and progesterone receptor (PR) hormone receptor negativity (Table 2). The gene discussed is ESR1; the disease is neoplasm.