BDNF and primary biliary cholangitis: In patients with PBC, plasma BDNF concentrations correlated negatively with liver stiffness measured by elastography (R = −0.394, p = 0.0258), splenic index (R = −0.432, p = 0.0054), splenic vein diameter (R = −0.449, p = 0.005), and splenic vein flow volume (R = −0.489, p = 0.0018) (Figure 2).