Among the immune cell populations of the innate immunity, macrophages of the M2 phenotype showed a negative correlation with the co-expression of PEBP1/STK11 in several cancer types, including colorectal adenocarcinoma (COAD), bladder urothelial carcinoma (BLCA), chromophobe renal cell carcinoma (KICH), KIRC, GBM, and lung squamous cell carcinoma (LUSC). This evidence concerns the gene STK11 and cancer.