In contrast, genes such as ALDH2, LDHB, SLC7A5, SLC3A2, and HPRT1 displayed more complex patterns, with both positive and negative correlations observed in relation to PEBP1/STK11 co-expression, indicating that these genes might be part of more dynamic metabolic processes and reprogramming that fluctuate depending on the tumor type and the PEBP1/STK11 expression levels. The gene discussed is HPRT1; the disease is neoplasm.