Accordingly, pro-inflammatory chemokine genes exhibited a broad negative correlation with PEBP1/STK11 co-expression across cancers of the gastrointestinal, reproductive, nervous, respiratory, and hematopoietic systems, suggesting that PEBP1/STK11 a potential role for in dampening inflammatory signaling within these malignancies (Figure 4B). This evidence concerns the gene STK11 and cancer.