In our study, several key immunoregulatory genes related to bacterial infection were upregulated, including ZNFR1, involved in TLR4 signaling induced by Gram-negative bacteria; BACH, involved in the adaptive immune response; and CXCL1, a chemokine that promotes neutrophil recruitment and has recently been shown to increase earlier than CRP in children with cancer and bacteremia. This evidence concerns the gene CXCL1 and bacterial infectious disease with sepsis.