Our analysis identified the TNF signaling pathway (p = 1.08 × 10−6), insulin resistance (p = 4.91 × 10−5), and Hippo signaling pathway (p = 9.80 × 10−5) as the most significantly enriched pathways, exhibiting notable impact values (e.g., 0.68 for insulin resistance) (Figure 6A, Table S9). This evidence concerns the gene TNF and Insulin resistance.