About CoVs, AhR is upregulated by infections due to both alpha-CoVs, including HCoV-229E, canine coronavirus (CCoV), porcine epidemic diarrhea virus (PEDV), as well as feline coronavirus (FCoV), and beta-CoVs, like mouse hepatitis virus (MHV), HCoV-OC43, MERS-CoV, SARS-CoV-1, SARS-CoV-2, and BCoV [28,29,30,31,32,33,34,35,36]. The gene discussed is AHR; the disease is infection.