EMT is the initial stage in cancer metastasis [1,35], and the EMT activator Zeb1 has been identified as a key factor in promoting metastasis formation in various types of cancer, including hepatocellular carcinoma and pancreatic, prostate, colorectal, and breast cancers [18,19,31,36,37,38]. Here, ZEB1 is linked to hepatocellular carcinoma.