Regarding the relationship between lipogenesis-related genes and clinical and metabolic parameters, quantile regression adjusted for sex, age, and obesity revealed that SREBP1 was negatively associated with glucose (β = −0.020; p = 0.026), insulin (β = −0.012; p = 0.030), and HOMA-IR (β = −0.050; p = 0.049). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.