UPF1 and major depressive disorder: After including selected covariates, participants with depression remained significantly more likely to have diabetes (OR: 1.258, 95% CI: 1.064 to 1.489 for UPF1, and OR: 1.251, 95% CI: 1.059 to 1.478 for UPF2), the association between high UPF consumption and a lower likelihood of diabetes remained significant under the UPF1 definition (OR: 0.547, 95% CI: 0.495 to 0.605), while this association was no longer significant under the UPF2 definition (OR: 0.796, 95% CI: 0.571 to 1.109).