Treatment with the flavonoid, procyanidin, led to higher relative abundance levels of Lachnospiraceae_UCG-006 and was positively correlated with CD8 T-cells in lung metastatic female mice, suggesting a link between Lachnospiraceae_UCG-006 and the immune response to C26 colon cancer cell metastasis [56]. The gene discussed is CD8A; the disease is malignant colon neoplasm.