Cisplatin-triggered ferroptotic tumor cells reprogram TANs toward an N1-like phenotype, characterized by the upregulation of cytotoxic effectors such as TNF-α, granzyme B, and NE, as well as chemokines and cytokines including CCL2, CCL3, CXCL9, CXCL10, CXCL11, IL-12A, and IL-12B. This evidence concerns the gene CCL2 and neoplasm.