Head and Neck Cancer and Esophageal Cancer: When analyzing the effect of imprinted genes on the prognosis of squamous cell carcinoma of the head and neck (SCCHN), Hsu and colleagues observed that higher expression of CPA4 was related to poor survival (p < 0.01) in 73 patients with SCCHN [33]. This evidence concerns the gene CPA4 and head and neck squamous cell carcinoma.