BARD1 and breast carcinoma: Another study found an OR of 3.2 (p-value = 0.012; n = 2127) for breast cancer patients with a family history of breast cancer, while a large-scale case–control study indicated an OR of 2.3 (p-value = 0.04; n = 13,935) [3,29], showing that BARD1 is associated with low to moderate risk for breast cancer.