A significant increase in the family history of liver cancer was observed in BARD1-mutated families compared to BRCA1-mutated families; 33% of BARD1 mutation carriers had a family history of liver cancer, whereas only 11.6% and 11.3% of BRCA1 mutation carriers and non-carriers did, respectively (p-value = 0.049 and 0.04). This evidence concerns the gene BARD1 and liver cancer.