Whereas Ren et al. reported BRAF mutations in 81.9% of Chinese PTCs without connecting them to specific management pathways, our multivariate analyses demonstrate that BRAF-like mutations are strongly associated with lymph node metastasis (OR = 3.25, p = 0.008) and tumor size > 4 cm (OR = 17.45, p < 0.001). This evidence concerns the gene BRAF and neoplasm.