This study found that after feeding goldfish with AB-WE and challenging them with pathogenic bacteria, antioxidant-related factors (CAT, SOD, MDA, and GSH-Px) decreased in serum, indicating that AB-WE reduced the oxidative stress response caused by bacterial infection in goldfish, suggesting that AB-WE possesses antioxidant activity. The gene discussed is SOD1; the disease is bacterial infectious disease.