Additionally, a meta-analysis reported a significant connection between elevated RDW and AF pathogenesis, while, at the same time, RDW is the only hematological parameter that is found consistently elevated in CHIP carriers, potentially indicating underlying disruptions in erythropoiesis or hematopoiesis in general, which both represent characteristic features of CHIP [98,99]. Here, STUB1 is linked to atrial fibrillation.