TNNT2 and heart disorder: However, there are important differences between the two markers, for example, in patients with skeletal muscle disorders, it is possible for patients to have fairly normal troponin I with a higher hs-cTnT even in the absence of cardiac disease, for example, in noninflammatory myopathies/myositis/myasthenic syndrome (hs-cTnT can be up to 16 ng/L higher in patients with muscular complaints versus control subjects) [6], neuromuscular disease such as amyotrophic lateral sclerosis [7] and rhabdomyolysis [8].