To study the effects of renal dysfunction on the HISCL hs-cTnT assay, results were correlated with subjects by CKD stage (subjects with eGFR <60 mL/min/1.73 m2: Males/Females 152/151, age 37–99 years old, age median 77 years old, CKD-EPI eGFR range 2–59 mL/min/1.73 m2, no subjects on dialysis yet). This evidence concerns the gene TNNT2 and chronic kidney disease.