Western blot analysis revealed that the expression levels of mitochondrial fusion proteins MFN1 and Opa1 were notably lower in the DCM group compared to the control group (p < 0.05), whereas the expression of the mitochondrial fission protein p-Drp1Ser616 was significantly higher (p < 0.05). The gene discussed is OPA1; the disease is familial dilated cardiomyopathy.