BCL2 and AL amyloidosis: BCL-2 is an antiapoptotic molecule that is being overexpressed in several myeloid diseases such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but also in several lymphoid cancers such as acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), non-Hodgkin lymphomas, and multiple myeloma (MM) [2–6].