In addition to Western blotting and qRT-PCR analysis, the histological examination using H&E staining showed TP-0903 administration reduced the number of xenografted NB cells, and the IHC staining also revealed that the expression of cell proliferation marker Ki-67 and DKK1 were decreased in tumor tissues in response to TP-0903 administration (Fig. 6G). The gene discussed is MKI67; the disease is neoplasm.