Such an increment in serum AST could be responsible for the excess release of AST from damaged non-hepatic muscle cells (erythrocytes, kidney and brain tissue, cardiac and skeletal muscle) during dengue.1 ALT is mainly related with hepatocytes and is elevated because of damage to liver cells, indicating hepatic damage.11 Nevertheless, such increments show the degree of hepatocellular injury and suggest significant liver damage; therefore, they can be used as a potential marker to identify the disease. The gene discussed is GPT; the disease is dengue disease.