Interestingly, the RNA-seq data revealed reduced expression of not only DNAJC7 but also the HSP70 family, including HSAPA1A, HSAPA1B, and HSAPA6 in the brain, which is consistent with a previous report showing HSP70 expression was decreased in sporadic ALS patient spinal cord [14]. The gene discussed is DNAJC7; the disease is amyotrophic lateral sclerosis.