STAT3 and neuroblastoma: Although some studies have suggested that MeHg induced STAT3 phosphorylation in vitro in N9 microglial, SH-SY5Y neuroblastoma, mouse cortical neuronal progenitor, and in GT1-7 hypothalamic neuronal cells [18, 20, 21], and in vivo in the brain of Wistar rats and the hypothalami of C57BL/6 mice [19, 24], its role in MeHg toxicity is not fully understood.