The most promising combination of oculomotor endpoints was selected for all other HCAs, with either two (FRDA, RFC1-related ataxia, SCA27B, AOA1, AOA2), three (SCA1, SCA3, SCA7, EA2) or four (SCA6, A-T) oculomotor domains. The gene discussed is RFC1; the disease is cerebellar ataxia.