INTS8 and lung adenocarcinoma: Finally, by integrating the results of PPI network analysis and one-way COX regression analysis, we identified six RBPs that are both DEGs and associated with lung adenocarcinoma prognosis—IGF2BP3, SNRPE, GAPDH, MRPL12, MRPL15, and INTS8, with IGF2BP3 being the most differentially expressed (Figure 1G).