IL1B and Mental deterioration: Knowing all the published data regarding the driving power of IL-1β and the related inheritance of the Alzheimer gene as reported here, it is particularly curious, in the face of the ultimate failure of improvement in forestalling further cognitive decline in even one of the many human trials aimed at clearance of Aβ plaques in the human brain, that, relatively speaking, trials have neglected to aim at the power of neuroinflammation and the Alzheimer’s gene as provocateurs of the neuropathogenesis of Alzheimer’s.