This correlation—while derived from separate tissue samples—is consistent with prior reports implicating Homer1a in the disruption of synaptic scaffolding and the attenuation of mGluR-mediated signaling, both of which are central to the altered synaptic plasticity and connectivity observed in neurodevelopmental disorders [59,60,61,62,63,64]. The gene discussed is HOMER1; the disease is neurodevelopmental disorder.