The administration of this substance allows for the representation of symptoms and features of sAD in animals, such as neuroinflammation, oxidative stress [14], disturbances of insulin signaling in the brain, insulin-resistant brain state (IRBS) [15] changes in the activity of enzymes involved in cerebral glucose metabolism [16], and also behavioral disturbances related to spatial memory, anxiety, and anhedonia disorders [17,18,19,20,21]. The gene discussed is INS; the disease is Anxiety.