Of the 213 AMD-associated genes in our samples, 13 were involved in the proteostasis network (MARK4, ATP6V0D1, DAPK3, SNX7, BAG6, HERPUD1, NPLOC4, TOMM40, RPL3, HERC2, BARD1, BRAP and DPP9). This evidence concerns the gene BRAP and age-related macular degeneration.