Nevertheless, the increasing recognition of myelin dysfunction and oligodendrocyte alterations in human PD brain tissue and other non-MPTP PD models (e.g., alpha-synucleinopathy models) [30,31] suggests that the observed STAT5B-mediated myelin impairment in our study may represent a relevant pathological feature in a broader spectrum of PD etiologies. This evidence concerns the gene STAT5B and synucleinopathy.