Similar to previous observations in M. elsdenii‐colonized mice, FMT of ME‐H gut microbiota of CRC donors led to more severe pathological changes (Figure 8H), along with higher levels of DC activation‐related inflammatory cytokines Il1b and Il23, increased infiltration of CD11c+ DC number, and elevated Th1 and Th17 responses (Figure S8H–J, Supporting Information). The gene discussed is IL1B; the disease is colorectal carcinoma.