As shown in Figure 3E,F, SRC of CD4+ T cells in moderate and severe SLE groups (695.72 ± 63.88 and 884.31 ± 57.69 pmol/min) was significantly increased compared with HCs (161.54 ± 80.83 pmol/min, both p < 0.001), as well as basal respiration, maximal respiration, proton leak, and ATP production (Figure S3E–H). Here, CD4 is linked to systemic lupus erythematosus.