CD4 and systemic lupus erythematosus: Compensatory glycolysis of CD4+ T cells in mild, moderate, and severe SLE groups (668.77 ± 283.97, 2874.94 ± 312.06, and 3657.59 ± 273.23 pmol/min) was significantly increased compared with controls (401.11 ± 77.76 pmol/min, all p < 0.05; Figure 3G,H), as well as basal glycolysis and basal proton efflux rate (Figure S4C,D).