Among them, 13 genes, including AHR, BCL2L1, CCND1, KRAS, SOX4, MYC, and E2F family genes, were previously reported to have increased expression in BC tissue [21, 22, 29, 30], and their alterations, either through amplification or upregulation, are linked with bladder tumor initiation or progression. This evidence concerns the gene SOX4 and urinary bladder neoplasm.