A more recent single-molecule photobleaching analysis of KRAS4B mutants isolated from Expi293 cells in native lipid nanodiscs found that dimers are more abundant in G12D and Q61H than in WT and that the dimer fraction is higher in KRAS4B G12V pancreatic adenocarcinoma (PDAC) cells than in their WT counterpart [65]. This evidence concerns the gene KRAS and pancreatic adenocarcinoma.