Although this lectin-mediated route in malaria is less clearly established and may depend on specific glycosylation patterns of both IgA and parasite antigens (Ding et al., 2022), complement activation of any type can culminate in opsonization and formation of membrane attack complexes (Kurtovic et al., 2018; Owuor et al., 2008). This evidence concerns the gene CD79A and malaria.