CD79A and infection: However, shifting perspectives reveal that parasite-specific IgA can indeed arise in natural and experimental malaria infections (Berry et al., 2021; Tan et al., 2021), prompting new questions about its potential to neutralize sporozoites early in infection, engage the alternative and lectin complement pathways, and modulate inflammatory responses (Rogier et al., 2022; Shi et al., 2011).