ATG7 and liver dysplastic nodule: For example, in a DN rat model, circ_ATG7 derived from urinary stem cells (USCs) was significantly downregulated, overexpression of circ_ATG7 significantly alleviated kidney damage in DN rats; however, after knocking out circ_ATG7 derived from USCs, the improvement in kidney function and therapeutic effect in DN rats were lost (143).