demonstrated significantly down-regulated miR-204-5p and up-regulated SNAI1 and lncRNA-CLYBL-AS2 in the serum of DN patients and murine models, CLYBL-AS2 exhibited a negative correlation with miR-204-5p and a positive association with SNAI1 expression and DN staging (161). The gene discussed is SNAI1; the disease is liver dysplastic nodule.