NPPB and Sepsis: Frencken et al. (2018) found that elevated troponin levels were independently associated with mortality within 14 days among sepsis patients with myocardial injury; But this association did not persist beyond 14 days, regardless of whether troponin levels were mildly, moderately, or highly elevated. Brueckmann et al. (2005) reported that sepsis patients with NT-proBNP levels exceeding 1400 pmol/L had a 3.9-fold higher risk of death compared to those with lower levels (RR = 3.9; 95% CI, 1.6 to 9.7).