Lu et al. identified 25 candidate metabolites in F. Choerospondiatis, mainly including organic acids, phenolic acids, flavonoids, etc., 38 metabolites in M. fragran, including volatile oils, terpenoids, phenols, etc. Network pharmacological analysis predicted that these metabolites could bind to 89 coronary heart disease (CHD)-related targets, such as MAPK14/p38, TP53/p53, F2, etc. These targets are involved in the networks of stress responses, cell adhesion and connections, angiogenesis, and other key CHD-related biological processes (Lu et al., 2018). Here, TP53 is linked to coronary artery disorder.