The docking results of caffeic acid (CA) and benzyl isothiocyanate (BITC) with key cancer-related receptor proteins—including ERK2 (PDB: 4QTB), p38 MAPK (PDB: 3GCU), Bcl-2 (PDB: 4MAN), Keap1-Nrf2 complex (PDB: 5YWE), and GST (PDB: 1ZHA)—revealed strong binding interactions. This evidence concerns the gene NFE2L2 and cancer.