These CXCL13+CD8+PD-1+TIGIT+ T cells, referred to as effector-like CD8+ Tex cells, are characterized by robust cytotoxicity, secretion of inflammatory cytokines and chemokines, and strong association with antitumor immune responses, suggesting their involvement in effective tumor control cells (40, 41). This evidence concerns the gene CXCL13 and neoplasm.