MYOD1 and cancer: Given that MyoD regulates DMNTs and CYLD was predicted to contain a CpG island, we then analyzed methylation of the CYLD gene using the Cancer Cell Line Encyclopedia (CCLE) dataset, generated from the Illumina Infinium HumanMethylation450 (450K) BeadChip array platform, which targets 96% of CpG islands in the human genome.53