A comparative analysis of 120 DEGs identified in sarcoidosis and 1,256 DEGs in LC revealed twelve genes (SALL4, WNT10A, RASAL1, CAMK2B, GADD45B, KLF4, OLR1, CSF3, WIF1, RAMP3, AGER, and PRKAG3) that were commonly altered in both diseases compared to their respective controls. Here, KLF4 is linked to sarcoidosis.