Moreover, the frequencies of CD8+ and CD4 + T cells, and the relative abundance of naïve T cells (CD44-CD52L+), effector/memory T cells (CD44+CD62L−), and central memory T cells (CD44+CD62L+) cells was unaffected in the tumor-draining lymph nodes (Fig. 5F–Q). Here, CD44 is linked to neoplasm.