mRNA expression of proinflammatory cytokines(IL-6, IL-1β), growth factors (GM-CSF, M-CSF), matrix metalloproteinase (MMP-1, MMP-3), chemokines (CCL2, CX3CL1), extracellular matrix proteins (Col1a1, Col1a2, Col3a1, fibronectin-1, tenascin-C) and phenotypic markers (fibroblast activation protein [FAP], podoplanin [PDPN], α-smooth muscle actin, CD200) in cultured fibroblasts were examined by qPCR.<h4>Results</h4>In GCA-affected arteries, pro-inflammatory CD90+IL-6+ fibroblasts, but not pro-resolving CD90+CD200+ fibroblasts, were spatially associated with macrophages. Here, MMP1 is linked to temporal arteritis.