LGALS3 and glaucoma: Further, they found that the Mitotracker signal was found largely within the distended processes of astrocytes that express high levels of Lgals3, the gene whose expression in astrocytes initially led us to the discovery of the transcellular degradation process, and which we had also shown increases in a different glaucoma model, DBA2/J mice (Nguyen et al., 2011).