Hence, except for these four patients with nonmeasurable neuroblastoma, every other patient with IHC-evaluable specimens submitted for screening had tumors that expressed B7-H3, including all cases of measurable neuroblastoma, osteosarcoma, rhabdomyosarcoma, DRSCT, and Ewing sarcoma and all 13 patients with other, less common solid tumors. Here, CD276 is linked to Ewing sarcoma.