SMARCB1 and schwannoma: Taken together, the conditional knockout mouse models established by Vitte et al. [179] indicated that Smarcb1 loss at a later developmental stage (starting at E13.5) in the Schwann cell lineage, in addition to biallelic Nf2 gene inactivation, results in schwannomas in mGFAP-Cre; Smarcb1flox/flox;Nf2flox/flox mice.