In the same study, circulating eotaxin-2 was found higher in patients with NAFLD and fibrosis-4 (FIB-4) > 1.45 compared to controls, implying a potential activation of the CCL24-CCR3 axis in the advanced stages of NAFLD [161], which, however, needs histological confirmation. This evidence concerns the gene CCR3 and metabolic dysfunction-associated steatotic liver disease.