Within the context of MASLD, various cell types (i.e., KCs, infiltrating macrophages, hepatocytes, and activated HSCs) [130] produce MCP-1, which attracts C-C chemokine receptor type 2 (CCR2)+ monocytes within the liver, possibly promoting hepatic steatosis and fibrosis [131, 132]. Here, CCL2 is linked to metabolic dysfunction-associated steatotic liver disease.