IL10 and metabolic dysfunction-associated steatotic liver disease: In a study of NAFLD mice, although HFD feeding polarized KCs toward a pro-inflammatory state, the interaction between the hepatic invariant NKT (iNKT) cells and CD170+ KC-1 subset enhanced the KC-1-mediated expression of IL-10, thus possibly acting as a counterbalancing mechanism aiming to maintain immune balance in the liver and to protect against diet-induced MASLD [89].