Eotaxin (CCL11), an eosinophil-attracting chemokine, has been recognized as a regulator of NAFLD since it was shown to increase in the liver of three different NAFLD mice models (C57/B6 mice on a HFHC diet, Apoe−/− mice on a Western diet, and db/db mice on an MCD diet). Here, APOE is linked to metabolic dysfunction-associated steatotic liver disease.