IL1B and Hepatic fibrosis: A meta-analysis encompassing 36,074 NAFLD patients and 47,052 controls showed that IL-1β was associated with NASH [odds ratio (OR) = 1.08, 95% CI = 1.01–1.15] and hepatic fibrosis (OR = 1.16, 95% CI = 1.04–1.29) [27].