Interestingly, both Fas and FasL have been incorporated in prediction models of NASH [e.g., the “NASH apoptosis score” including FasL, transferrin, ferritin, age, and triglycerides, as well as the combination of Fas with cytokeratine-18 (CK-18)] [42, 44]. This evidence concerns the gene KRT18 and metabolic dysfunction-associated steatohepatitis.